马长乐
日期: 2017/04/19 作者: 浏览量:
马长乐
个人简介
马长乐,122cc太阳集成游戏教授,泰山学者,山东省逆境植物重点实验室主任。长期致力于过氧化物酶体生物发生和自噬以及植物耐盐分子生物学方面的研究。目前已有40余篇发表在, Autophagy, Plant Cell, Plant Physiology,Journal of Cell Biology,Journal of Biological Chemistry, Trends in Plant Science等期刊上,总引用约1800次(Google Scholar数据)。
教育经历
(1) 2002.6–2006.1,德国哥廷根大学,博士
(2) 1999.9–2002.5,122cc太阳集成游戏,硕士
(3) 1995.9–1999.7,122cc太阳集成游戏,学士
工作经历
(1) 2013.1-至今,122cc太阳集成游戏,122cc太阳集成游戏,教授
(2) 2011.3-2013.1,美国加州大学圣地亚哥分校,122cc太阳集成游戏,研究助理教授
(3) 2007.1-2011.2,美国加州大学圣地亚哥分校,122cc太阳集成游戏,博士后
(4) 2006.1-2006.12,德国哥廷根大学,植物生物化学系,博士后
承担的主要项目:
国家自然基金面上项目:拟南芥自噬受体PDF1调控过氧化物酶体降解的分子机理研究, 2020.01-2023.12,主持, 59万
国家自然基金面上项目:“酿酒酵母酪蛋白激酶CK2调控过氧化物酶体生物发生的分子机理研究”, 2017.01-2018.12,主持, 25万
山东省“渤海粮仓”项目:耐盐藜麦品种(系)的选育与配套关键技术研发和示范应用,2019.08-2022.08,主持, 160万
山东省良种工程课题:小麦基因编辑技术, 2019.08-2022.08,主持, 270万
主要科研成果:
Fu C#, Liu X#, Li X#, Huo P, Ge J, Hou Y, Yang W, Zhang J, Zhang L, Zhao D, Ma C*, Liu J*. BRF Negatively Regulates Thermotolerance Defect of fes1a in Arabidopsis. Front Plant Sci. 2020 Mar 10;11:171. doi: 10.3389/fpls.2020.00171.
Su T#, Li X#, Yang M, Shao Q, Zhao Y, Ma C*, Wang P*. Autophagy: An Intracellular Degradation Pathway Regulating Plant Survival and Stress Response. Front Plant Sci. 2020 Feb 28;11:164. doi: 10.3389/fpls.2020.00164.
Yang X, Feng T, Li S, Zhao H, Zhao S, Ma C, Jenks MA, Lü S*. CER16 Inhibits Post-Transcriptional Gene Silencing of CER3 to Regulate Alkane Biosynthesis. Plant Physiol. 2020 Mar;182(3):1211-1221. doi: 10.1104/pp.19.01002.
Shao Q, Liu X, Su T, Ma C*, Wang P*. New Insights Into the Role of Seed Oil Body Proteins in Metabolism and Plant Development. Front Plant Sci. 2019 Dec 10;10:1568. doi: 10.3389/fpls.2019.01568.
Jia Y#, Tian H#, Zhang S, Ding Z*, Ma C*. GUN1-Interacting Proteins Open the Door for Retrograde Signaling. Trends Plant Sci. 2019 Oct;24(10):884-887. doi: 10.1016/j.tplants.2019.07.005.
Hua K, Zhang J, Botella JR, Ma C, Kong F, Liu B, Zhu JK*. Perspectives on the Application of Genome-Editing Technologies in Crop Breeding. Mol Plant. 2019 Aug 5;12(8):1047-1059. doi: 10.1016/j.molp.2019.06.009.
Su T, Li W, Wang P, Ma C*. Dynamics of Peroxisome Homeostasis and Its Role in Stress Response and Signaling in Plants. Front Plant Sci. 2019 Jun 4;10:705. doi: 10.3389/fpls.2019.00705.
Zhou Y, Li P , Fan N , Wang X , Liu X , Wu L , Zhang W , Zhang W , Ma C*, Tang B*. In situ visualization of peroxisomal peroxynitrite in the livers of mice with acute liver injury induced by carbon tetrachloride using a new two-photon fluorescent probe. Chem Commun (Camb). 2019 Jun 6;55(47):6767-6770.
Wang X#, Wang P#, Zhang Z, Farré JC, Li X, Wang R, Xia Z, Subramani S, Ma C*. The autophagic degradation of cytosolic pools of peroxisomal proteins by a new selective pathway. Autophagy. 2020 Jan;16(1):154-166. doi: 10.1080/15548627.2019.1603546.
Wang X, Li S, Liu Y, Ma C*. Redox regulated peroxisome homeostasis. Redox Biol. 2015;4:104-8.
Shen X#, Wang Z#, Song X, Xu J, Jiang C, Zhao Y*, Ma C*, Zhang H*. Transcriptomic profiling revealed an important role of cell wall remodeling and ethylene signaling pathway during salt acclimation in Arabidopsis. Plant Mol Biol. 2014 Oct;86(3):303-17.
Hagstrom D#, Ma C#*, Guha-Polley S, Subramani S*. The unique degradation pathway of the PTS2 receptor, Pex7, is dependent on the PTS receptor/coreceptor, Pex5 and Pex20.Mol Biol Cell. 2014 Sep 1;25(17):2634-43.
Ma C, Hagstrom D, Polley SG, Subramani S. Redox-regulated cargo binding and release by the peroxisomal targeting signal receptor, Pex5.J Biol Chem. 2013 Sep 20;288(38):27220-31.
Liu X, Ma C, Subramani S*. Recent advances in peroxisomal matrix protein import. Current Opinion in Cell Biology. 2012 Aug, 24(4):484-9
Ma C#, Agrawal G#, Subramani S*. Peroxisome assembly: matrix and membrane protein biogenesis. J Cell Biol. Apr 4; 193(1):7-16.
Babujee L, Wurtz V, Ma C,Lueder F, Soni P, van Dorsselaer A, Reumann S*. The proteome map of spinach leaf peroxisomes indicates partial compartmentalization of phylloquinone (vitamin K1) biosynthesis in plant peroxisomes. J Exp Bo. 2010 Mar; 61(5):1441-53.
Ma C, Schumann U, Rayapuram N, Subramani S*. The peroxisomal matrix import of Pex8p requires only PTS receptors and Pex14p. Mol Biol Cell. 2009 Aug; 20(16):3680-9.
Ma C, Subramani S*. Peroxisome matrix and membrane protein biogenesis.IUBMB Life. 2009 Jul; 61(7):713-22.
Ma C, Reumann S*. Improved prediction of peroxisomal PTS1 proteins from genome sequences based on experimental subcellular targeting analyses as exemplified for protein kinases from Arabidopsis. J Exp Bot. 2008; 59(13):3767-79.
Reumann S*, Babujee L, Ma C, Wienkoop S, Siemsen T, Antonicelli GE, Rasche N, Lüder F, Weckwerth W, Jahn O. Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. Plant Cell. 2007 Oct; 19(10):3170-93.
Ma C, Haslbeck M, Babujee L, Jahn O and Reumann S*. Identification and Characterization of a Stress-Inducible And a Constitutive Small Heat Shock Protein Targeted to the Matrix of Plant Peroxisomes. Plant Physiol. 2006 May; 141(1):47-60.
Reumann S*, Ma C, Lemke S and Babujee L. Araperox. A database of putative Arabidopsis proteins from plant peroxisomes. Plant Physiol. 2004 Sep, 136(1):2587-2608.