姓名职称：

谢松波 教授，硕士生导师

教育经历：

2001/09-2005/07南开大学，122cc太阳集成游戏，本科，生物科学专业。

2006/09-2009/07南开大学，122cc太阳集成游戏，硕士，遗传学专业，导师：周军 教授。

2013/09-2016/07南开大学，122cc太阳集成游戏，博士，生物化学与分子生物学专业，导师：陈喜文/周军 教授

工作经历：

2009/07-2013/08康龙化成（北京）新药技术有限公司，生物部，研发组组长。

2016/09-2020/06 122cc太阳集成游戏，122cc太阳集成游戏，职位：讲师。

2020/07-今 山东理工大学，122cc太阳集成游戏，职位：教授。

研究兴趣，领域：

研究方向：细胞结构与功能

1. 细胞内动态结构成像；

2. 细胞骨架相关新技术的开发

3. 细胞骨架与人类疾病

主持或参加科研项目及人才计划项目情况：

1. 国家自然科学基金-青年科学基金：2018.01-2020.12，HDAC6调控巨噬细胞和中性粒细胞向炎症部位浸润的分子机理研究，25万，主持

2. 山东省自然科学基金-面上项目：2017.07-2020.06，细胞骨架动态性重塑对免疫吞噬细胞趋化运动的调节及机制研究， 18万，主持

3. 中国博士后科学基金-面上项目：2017.01-2018.12，HDAC6对细胞骨架动态性重塑和免疫细胞趋化运动的调控， 8万，主持

代表性论文：

1. Yan B^#, Xie S^#*, Liu Y^#, Liu W, Li D, Liu M, Luo HR, Zhou J*. Histone deacetylase 6 modulates macrophage infiltration during inflammation. Theranostics. 2018; 8(11):2927-2938.

2. Chen M, Wang J, Yang Y, Zhong T, Zhou P, Ma H, Li J, Li D, Zhou J, Xie S*, Liu M*. Redox-dependent regulation of end-binding protein 1 activity by glutathionylation. Sci China Life Sci. 2020. doi: 10.1007/s11427-020-1765-6

3. Xie S, Ogden A, Aneja R, Zhou J*. Microtubule-Binding Proteins as Promising Biomarkers of Paclitaxel Sensitivity in Cancer Chemotherapy. Med Res Rev. 2016; 36(2):300-12.

4. Tala^#, Xie S^#, Sun X^#, Sun X, Ran J, Zhang L, Li D, Liu M, Bao G*, Zhou J*. Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasis. Theranostics. 2014; 4(10):1052-61.

5. Xie S#*, Yan B#, Feng J, Wu Y, He N, Sun L, Zhou J, Li D, Liu M*. Altering microtubule stability affects microtubule clearance and nuclear extrusion during erythropoiesis. J Cell Physiol. 2019; 234(11):19833-19841.

6. Xie S*, Wu Y, Hao H, Li J, Guo S, Xie W, Li D, Zhou J, Gao J, Liu M*. CYLD deficiency promotes pancreatic cancer development by causing mitotic defects. J Cell Physiol. 2019; 234(6):9723-9732.

7. Xie S^#, Yang Y^#, Lin X^#, Zhou J, Li D, Liu M*. Characterization of a novel EB1 acetylation site important for the regulation of microtubule dynamics and cargo recruitment. J Cell Physiol. 2018; 233(3):2581-2589.

8. Xie S, Zhou J*. Harnessing Plant Biodiversity for the Discovery of Novel Anticancer Drugs Targeting Microtubules. Front Plant Sci. 2017; 8:720.

9. Xie S^#, Dong B^#, Sun X, Tala, He X, Zhou J, Liu M, Li D. Identification of a cytoplasmic linker protein as a potential target for neovascularization. Atherosclerosis. 2014; 233(2):403-9.

10. Li D^#, Xie S^#, Ren Y^#, Huo L, Gao J, Cui D, Liu M, Zhou J. Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner. Protein Cell. 2011; 2(2):150-60.

11. Chen M, Cao Y, Dong Dan, Zhang Z, Zhang Y, Chen J, Luo Y, Chen Q, Xiao X, Zhou J, Li D, Xie S*, Liu M*. Regulation of mitotic spindle orientation by phosphorylation of end binding protein 1. Exp Cell Res. 2019; 384(1):111618.

12. Xie S^#, Qin J^#, Liu S, Zhang Y, Wang J, Shi X, Li D, Zhou J, Liu M*. Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization. Sci Rep. 2016; 6:21263.